3-氨基-6-氯-4-甲基吡啶合成路线 （共 4 条）
反应条件
in water T=33°C; 73 h; baker's yeast;
参考文献
Takeshita, Mitsuhiro; Yoshida, Sachiko
Heterocycles, 1990 , vol. 31, # 12 p. 2201 - 2204
反应条件
acetic acid; sodium nitrite in water T=20°C;
参考文献
Chapman, David; Hurst, Jim
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2398 - 2404
反应条件
in toluene
T=100°C; 2 h;
参考文献
Chapman, David; Hurst, Jim
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2398 - 2404
反应条件
1: With hydrogenchloride; sodium nitrite in water
T=-5°C; 0.166667 h; Heating / reflux;
2: With thionyl chloride; copper(l) chloride in water
T=-5 - 20°C;
参考文献
ELAN PHARMACEUTICALS, INC.
Patent: WO2003/93245 A1, 2003 ;
Location in patent: Page/Page column 204-205 ;
WO 03/093245 A1
