4-吡咯烷基-1-吡啶-2-羧酸盐酸盐合成路线 (共 3 条)
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane
T=0 - 20°C; 6 h; Heating / reflux;
参考文献
Wieprecht, Torsten; Schlingloff, Gunther; Xia, Juntao; Heinz, Uwe; Schneider, Abert; Dubs, Marie-Josee; Bachmann, Frank; Hazekamp, Menno; Dannacher, Josef
Patent: US2006/19853 A1, 2006 ;
Location in patent: Page/Page column 20 ;
反应条件
1: With sodium hydroxide in water
2 h; Reflux;
2: With acetic acid
参考文献
Bogdanowicz, Agnieszka; Foks, Henryk; Gobis, Katarzyna; Augustynowicz-Kopec, Ewa
Heteroatom Chemistry, 2012 , vol. 23, # 2 p. 223 - 230
反应条件
1: 1,4-dioxane / 3 h / Reflux
2: sodium hydroxide / water / 2 h / Reflux
View Scheme
参考文献
Bogdanowicz, Agnieszka; Foks, Henryk; Gobis, Katarzyna; Augustynowicz-Kopec, Ewa
Heteroatom Chemistry, 2012 , vol. 23, # 2 p. 223 - 230