sodium hydroxide in ethanol 30 h; Ambient temperature;

1: 71.6 percent / K2CO3 / H2O; benzene / 3 h / 60 °C 2: SOCl2, DMF / 4 h / Ambient temperature 3: 91 percent / Et3N / CHCl3 / 3 h / Ambient temperature 4: 72 percent / 1 N NaOH / ethanol / 30 h / Ambient temperature View Scheme

1: 71.6 percent / K2CO3 / H2O; benzene / 3 h / 60 °C 2: SOCl2, DMF / 4 h / Ambient temperature 3: 91 percent / Et3N / CHCl3 / 3 h / Ambient temperature 4: 72 percent / 1 N NaOH / ethanol / 30 h / Ambient temperature View Scheme

1: SOCl2, DMF / 4 h / Ambient temperature 2: 91 percent / Et3N / CHCl3 / 3 h / Ambient temperature 3: 72 percent / 1 N NaOH / ethanol / 30 h / Ambient temperature View Scheme

1: 91 percent / Et3N / CHCl3 / 3 h / Ambient temperature 2: 72 percent / 1 N NaOH / ethanol / 30 h / Ambient temperature View Scheme