(3,4-二氨基苯)(4-氟苯)甲酮合成路线 （共 10 条）
反应条件
hydrogen; nickel in tetrahydrofuran P=3102.9 Torr; 7 h; Ambient temperature;
参考文献
Victor, Frantz; Brown, Thomas J.; Campanale, Kristina; Heinz, Beverly A.; Shipley, Lisa A.; Su, Kenneth S.; Tang, Joseph; Vance, Lori M.; Spitzer, Wayne A.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 10 p. 1511 - 1518
反应条件
hydrogen; nickel in tetrahydrofuran P=3102.9 Torr; 12 h;
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 24 p. 3937 - 3946
反应条件
1: t-BuOK / dimethylformamide / 4 h / Ambient temperature 2: 30percent aq. H2O2 / dimethylformamide / 0 - 20 °C 3: H2 / Raney nickel / tetrahydrofuran / 12 h / 3102.9 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 24 p. 3937 - 3946
反应条件
1: t-BuOK / dimethylformamide / 4 h / Ambient temperature 2: 30percent aq. H2O2 / dimethylformamide / 0 - 20 °C 3: H2 / Raney nickel / tetrahydrofuran / 12 h / 3102.9 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 24 p. 3937 - 3946
反应条件
1: PCl5 / 1.) RT, 10 min, 2.) RT to 45 deg C, 45 min 2: AlCl3 / 2 h / 50 °C 3: 92 percent / H2 / Raney nickel / tetrahydrofuran / 7 h / 3102.9 Torr / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 10 p. 1511 - 1518
反应条件
1: AlCl3 / 2 h / 50 °C 2: 92 percent / H2 / Raney nickel / tetrahydrofuran / 7 h / 3102.9 Torr / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 10 p. 1511 - 1518
反应条件
hydrogenchloride; hydrogen; platinum
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 28, # 4 p. 586 - 594
反应条件
1: (i) SOCl2, (ii) /BRN= 1236623/, AlCl3 2: NH3 3: H2, aq. HCl / Pt View Scheme
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 28, # 4 p. 586 - 594
反应条件
1: NH3 2: H2, aq. HCl / Pt View Scheme
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 28, # 4 p. 586 - 594
反应条件
1: (i) SOCl2, (ii) /BRN= 1236623/, AlCl3 2: NH3 3: H2, aq. HCl / Pt View Scheme
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 28, # 4 p. 586 - 594
