1-溴-3-(1-丙炔基)苯合成路线 （共 2 条）
反应条件
triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride in tetrahydrofuran; toluene
T=20°C; Inert atmosphere;
参考文献
ASTRAZENECA AB
Patent: US2012/165347 A1, 2012 ;
Location in patent: Page/Page column 29-30 ;
US 20120165347 A1
反应条件
1: 1-(3-bromophenyl)propanone With sodium hydride in tetrahydrofuran
T=0°C;
2: N,N-bis(trifluoromethanesulfonyl)aniline in tetrahydrofuran
T=0 - 20°C;
参考文献
Wallace, Debra J.; Klauber, David J.; Chen, Cheng-Yi; Volante, Ralph P.
Organic Letters, 2003 , vol. 5, # 24 p. 4749 - 4752
