反应条件
1: 1-bromo-3,4-dimethoxy-benzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 1 h; Inert atmosphere;
2: 1-Phenylmethyl-piperidin-4-one in tetrahydrofuran; hexane
T=-78 - 20°C; 3.5 h; Inert atmosphere; Further stages;
参考文献
Fujii, Hideaki; Okada, Kayoko; Ishihara, Marina; Hanamura, Shinichi; Osa, Yumiko; Nemoto, Toru; Nagase, Hiroshi
Tetrahedron, 2009 , vol. 65, # 51 p. 10623 - 10630
