(3-甲氧基-联苯-4-基)-乙酸合成路线 （共 4 条）
反应条件
sodium hydroxide in ethanol
1 h; Heating;
参考文献
Ghoneim, Ola M.; Legere, Jacqueline A.; Golbraikh, Alexander; Tropsha, Alexander; Booth, Raymond G.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 19 p. 6640 - 6658
反应条件
potassium carbonate; tris-(dibenzylideneacetone)dipalladium(0) in water
T=65°C; 2 h;
参考文献
Ghoneim, Ola M.; Legere, Jacqueline A.; Golbraikh, Alexander; Tropsha, Alexander; Booth, Raymond G.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 19 p. 6640 - 6658
反应条件
1: 80 percent / Na2CO3 / tetrakis(triphenylphosphine)palladium(0) / benzene; ethanol / 8 h / Heating
2: 85 percent / NaOH / ethanol / 1 h / Heating
View Scheme
参考文献
Ghoneim, Ola M.; Legere, Jacqueline A.; Golbraikh, Alexander; Tropsha, Alexander; Booth, Raymond G.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 19 p. 6640 - 6658
反应条件
1: 84 percent / p-toluenesulfonic acid / 7 h / Heating
2: 80 percent / Na2CO3 / tetrakis(triphenylphosphine)palladium(0) / benzene; ethanol / 8 h / Heating
3: 85 percent / NaOH / ethanol / 1 h / Heating
View Scheme
参考文献
Ghoneim, Ola M.; Legere, Jacqueline A.; Golbraikh, Alexander; Tropsha, Alexander; Booth, Raymond G.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 19 p. 6640 - 6658
