1-吗啉基-1-环己烯合成路线 （共 150 条）
反应条件
1: 72 percent / xylene / 2 h / 170 °C
2: 2) NH4OAc / 1) THF, hexane, 0 deg C, 3 h, 2) AcOH, reflux, 2 h
View Scheme
参考文献
Bell, Thomas W.; Cragg, Peter J.; Firestone, Albert; Kwok, Albert D.-I.; Liu, Jia; Ludwig, Richard; Sodoma, Andrej
Journal of Organic Chemistry, 1998 , vol. 63, # 7 p. 2232 - 2243
反应条件
(i) benzene, (ii) (acid hydrolysis); Multistep reaction;
参考文献
Hickmott,P.W.
Proceedings of the Chemical Society, London, 1964 , p. 287
反应条件
1: triethylamine / benzene / 168 h
2: hexachloroethane / benzene; petroleum ether
3: 5percent aq. carbonate / CHCl3
View Scheme
参考文献
Tolmachev, A. A.; Kostyuk, A. N.; Morozova, L. N.; Lampeka, R. D.; Kozlov, E. S.; Pinchuk, A. M.
J. Gen. Chem. USSR (Engl. Transl.), 1991 , vol. 61, # 7.2 p. 1607 - 1617,1475 - 1484
反应条件
1: With lithium boron tetrafluoride; [Ru(2,2′-bipyridine)3][hexafluorophosphate]2; 2,3,5,6-tetramethyl-p-benzoquinone in aceonitrile
T=20°C; 12 h; Inert atmosphereIrradiationMolecular sieve;
2: With water; ammonium chloride in acetonitrile
T=20°C; 1 h; Inert atmosphereMolecular sieve;
参考文献
Yasu, Yusuke; Koike, Takashi; Akita, Munetaka
Chemical Communications, 2012 , vol. 48, # 43 p. 5355 - 5357
反应条件
1: With lithium boron tetrafluoride; [Ru(2,2′-bipyridine)3][hexafluorophosphate]2; 2,3,5,6-tetramethyl-p-benzoquinone in aceonitrile
T=20°C; 12 h; Inert atmosphereIrradiationMolecular sieve;
2: With water; ammonium chloride in acetonitrile
T=20°C; 1 h; Inert atmosphereMolecular sieve;
参考文献
Yasu, Yusuke; Koike, Takashi; Akita, Munetaka
Chemical Communications, 2012 , vol. 48, # 43 p. 5355 - 5357
反应条件
1: N,N-dimethyl-formamide / 20 °C
2: water
View Scheme
参考文献
Cranwell, Philippa B.; O'Brien, Matthew; Browne, Duncan L.; Koos, Peter; Polyzos, Anastasios; Pena-Lopez, Miguel; Ley, Steven V.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 30 p. 5774 - 5779
反应条件
1: With lithium boron tetrafluoride; [Ru(2,2′-bipyridine)3][hexafluorophosphate]2; 2,3,5,6-tetramethyl-p-benzoquinone in aceonitrile
T=20°C; 12 h; Inert atmosphereIrradiationMolecular sieve;
2: With water; ammonium chloride in acetonitrile
T=20°C; 1 h; Inert atmosphereMolecular sieve;
参考文献
Yasu, Yusuke; Koike, Takashi; Akita, Munetaka
Chemical Communications, 2012 , vol. 48, # 43 p. 5355 - 5357
反应条件
in dichloromethane
72 h;
参考文献
Behringer,H.; Falkenberg,K.
Chemische Berichte, 1966 , vol. 99, p. 307 - 313
反应条件
ammonia in acetonitrile
T=100°C; Ring transformation; 3 h;
参考文献
Nishiwaki, Nagatoshi; Adachi, Tomoko; Matsuo, Kengo; Wang, Hui-Ping; Matsunaga, Tomoko; Tohda, Yasuo; Ariga, Masahiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 2000 , # 1 p. 27 - 32
反应条件
ammonia in acetonitrile
T=100°C; 3 h;
参考文献
Nishiwaki, Nagatoshi; Matsunaga, Tomoko; Thoda, Yasuo; Ariga, Masahiro
Heterocycles, 1994 , vol. 38, # 2 p. 249 - 252
