1-吗啉基-1-环己烯合成路线 （共 150 条）
反应条件
hydrogenchloride
1.) CHCl3, -15 deg C, 30 min, 2.) ether; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
May, George L.; Pinhey, John T.
Australian Journal of Chemistry, 1982 , vol. 35, # 9 p. 1859 - 1871
反应条件
in chlorobenzene
20 h;
参考文献
Behringer, Hans; Meinetsberger, Eike
Liebigs Annalen der Chemie, 1981 , # 10 p. 1729 - 1750
反应条件
in benzene
4 h; Heating;
参考文献
Crabb, Trevor A.; Jupp, Philip A.; Turner, Christopher H.
Organic Magnetic Resonance, 1984 , vol. 22, # 7 p. 424 - 427
反应条件
hydrogenchloride in diethyl ether
3 h;
参考文献
Crabb, Trevor A.; Turner, Christopher H.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1778 - 1782
反应条件
in 1,4-dioxane
16 h; RefluxInert atmosphereSchlenk technique;
参考文献
Kourkoulos, Dimitrios; Karakus, Cueneyt; Hertel, Dirk; Alle, Ronald; Schmeding, Sebastian; Hummel, Johanna; Risch, Nikolaus; Holder, Elisabeth; Meerholz, Klaus
Dalton Transactions, 2013 , vol. 42, # 37 p. 13612 - 13621
反应条件
triethylamine in dichloromethane
2 h; Ambient temperature;
参考文献
Fioravanti, Stefania; Loreto, M. Antonietta; Pellacani, Lucio; Tardella, Paolo A.
Journal of Organic Chemistry, 1985 , vol. 50, # 25 p. 5365 - 5368
反应条件
1: NaOMe / (anodic oxidation)
2: aq. HCl / CHCl3
3: aq. KOH / methanol
4: 180 °C
View Scheme
参考文献
Chiba,T. et al.
Journal of Organic Chemistry, 1979 , vol. 44, p. 3519 - 3523
参考文献
Allan
Australian Journal of Chemistry, 1979 , vol. 32, # 11 p. 2507 - 2516
反应条件
hydrogenchloride; potassium carbonate
Yield given. Multistep reaction;
参考文献
Terada, Atsusuke; Naruto, Shunji; Wachi, Kazuyuki; Tanaka, Shigeru; Iizuka, Yoshio; Misaka, Eiichi
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 212 - 216
反应条件
1: N-(1H-benzotriazol-1-ylmethyl)benzamide With zinc dibromide in dichloromethane
Elimination; 2 h; Heating;
2: 1-morpholino-cyclohexene With zinc dibromide in dichloromethane
amidoalkylation; 20 h; Heating;
参考文献
Katritzky, Alan R.; Fang, Yunfeng; Silina, Alina
Journal of Organic Chemistry, 1999 , vol. 64, # 20 p. 7622 - 7624
