1: 4-phenyl-1H-imidazole With sodium hydride in tetrahydrofuran
0.5 h; Inert atmosphere;
2: benzyl bromide in tetrahydrofuran
3 h;
参考文献
Kumar, Sanjeev; Jaller, Daniel; Patel, Bhumika; LaLonde, Judith M.; DuHadaway, James B.; Malachowski, William P.; Prendergast, George C.; Muller, Alexander J.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 16 p. 4968 - 4977
Kumar, Sanjeev; Jaller, Daniel; Patel, Bhumika; LaLonde, Judith M.; DuHadaway, James B.; Malachowski, William P.; Prendergast, George C.; Muller, Alexander J.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 16 p. 4968 - 4977
triethylamine in benzene
2 h; Heating; Yield given. Further byproducts given;
参考文献
Grassi, Giovanni; Foti, Francesco; Risitano, Francesco; Bruno, Giuseppe; Nicolo, Francesco; Munno, Giovanni De
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 21 p. 2615 - 2620
triethylamine in benzene
2 h; Heating; Yield given. Further byproducts given;
参考文献
Grassi, Giovanni; Foti, Francesco; Risitano, Francesco; Bruno, Giuseppe; Nicolo, Francesco; Munno, Giovanni De
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 21 p. 2615 - 2620
