2-氨基-5-甲氧基苯甲酸合成路线 （共 68 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; 24 h;
参考文献
Marks, Andrew R.; Landry, Donald W.; Deng, Shi Xian; Cheng, Zhen Zhuang
Patent: US2005/215540 A1, 2005 ;
Location in patent: Page/Page column 37 ;
反应条件
1: With sodium N-bromobenzenesulfonamide; sodium hydroxide; palladium dichloride in water; acetonitrile T=60°C; pH=12; 3.33333 h; 2: in water Acidic conditions;
参考文献
Karthikeyan; Jagadeesh, Rajenahally V.; Sree Sandhya; Puttaswamy; Nithya; Kumar, S. Senthil; Bhagat
Applied Organometallic Chemistry, 2011 , vol. 25, # 1 p. 34 - 46
反应条件
1: With sodium N-bromobenzenesulfonamide; sodium hydroxide; palladium dichloride in water; acetonitrile T=60°C; pH=12; 2.16667 h; 2: in water Acidic conditions;
参考文献
Kumar, C. Vinod; Shivananda; Raju, C. Nagu; Jagadeesh
Synthetic Communications, 2010 , vol. 40, # 23 p. 3480 - 3487
反应条件
hydrogenchloride T=100°C; 24 h;
参考文献
Maggi, Raimondo; Schlosser, Manfred
Journal of Organic Chemistry, 1996 , vol. 61, # 16 p. 5430 - 5434
反应条件
1: 58.6 percent / aq. NaOH 2: 34 percent / KMnO4, pyridine / H2O / 6 h / Heating 3: 97.5 percent / H2 / 10percent Pd/C / ethyl acetate / 1 h / 760 Torr / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 24, # 4 p. 533 - 548
反应条件
1: 34 percent / KMnO4, pyridine / H2O / 6 h / Heating 2: 97.5 percent / H2 / 10percent Pd/C / ethyl acetate / 1 h / 760 Torr / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 24, # 4 p. 533 - 548
反应条件
sulfuric acid Behandeln des erhaltenen 5-Methoxy-isatins mit wss. Natronlauge und wss. Wasserstoffperoxid;
参考文献
Journal of the American Chemical Society, , vol. 68, p. 1599,1601
反应条件
1: sodium sulfate; water; hydroxylamine hydrochloride 2: sulfuric acid / Behandeln des erhaltenen 5-Methoxy-isatins mit wss. Natronlauge und wss. Wasserstoffperoxid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 68, p. 1599,1601
反应条件
1: 1.) tert-butyllithium, N,N,N',N'-tetramethylethylenediamine / 1.) diethyl ether, -50 deg C, 2 h, 2.) diethyl ether 2: diethyl ether 3: 89 percent / hydrochloric acid / 24 h / 100 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 61, # 16 p. 5430 - 5434
反应条件
1: 80 percent / pyridine / CH2Cl2 / 20 h / Heating 2: 1.) tert-butyllithium, N,N,N',N'-tetramethylethylenediamine / 1.) diethyl ether, -50 deg C, 2 h, 2.) diethyl ether 3: diethyl ether 4: 89 percent / hydrochloric acid / 24 h / 100 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 61, # 16 p. 5430 - 5434
