(R)-2,2-二甲基 4-噻唑烷羧酸盐酸盐合成路线 （共 7 条）
参考文献
Kemp, D. S.; Carey, Robert I.
Journal of Organic Chemistry, 1989 , vol. 54, # 15 p. 3640 - 3646
反应条件
in acetone 6 h; Heating;
参考文献
Suaifan, Ghadeer A.R.Y.; Mahon, Mary F.; Arafat, Tawfiq; Threadgill, Michael D.
Tetrahedron, 2006 , vol. 62, # 48 p. 11245 - 11266
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=20°C; 18 h; Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 61, # 42 p. 10018 - 10035
反应条件
1: 2,2-dimethyl-L-thiazoline-4-carboxylic acid hydrochloride; N-Cbz-glycine fluoride With N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=20°C; 18 h; 2: methanol With chloro-trimethyl-silane T=20°C; 15 h;
参考文献
Tetrahedron, , vol. 61, # 42 p. 10018 - 10035
反应条件
1: (i) Py, CHCl3, (ii) /BRN= 471389/
2: diethyl ether; methanol / 12 h
View Scheme
参考文献
Iwakawa,M. et al.
Canadian Journal of Chemistry, 1978 , vol. 56, p. 326 - 335
反应条件
(i) Py, CHCl3, (ii) /BRN= 471389/; Multistep reaction;
参考文献
Iwakawa,M. et al.
Canadian Journal of Chemistry, 1978 , vol. 56, p. 326 - 335
反应条件
formic acid; acetic anhydride
T=20°C; 6 h;
参考文献
Bose, Partha Pratim; Drew, Michael G. B.; Banerjee, Arindam
Organic Letters, 2007 , vol. 9, # 13 p. 2489 - 2492
