(2-氧代-4-苯基吡咯烷-1-基)乙酸合成路线 （共 7 条）
反应条件
potassium hydroxide in ethanol 3 h; Heating;
参考文献
Glozman, O. M.; Morozov, I. S.; Zhmurenko, L. A.; Zagorevskii, V. A.
Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 11 p. 776 - 780
Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 11 p. 43 - 48
参考文献
Kramarova, E. P.; Shipov, A. G.; Orlova, N. A.; Artamkina, O. B.; Belavin, I. Yu.; Baukov, Yu. I.
J. Gen. Chem. USSR (Engl. Transl.), 1988 , vol. 58, # 5 p. 1093 - 1102,970 - 979
反应条件
1: 90 percent / conc. HCl / 0.33 h / Heating 2: 61 percent / 0.5 h / 150 - 160 °C 3: 99 percent / H2O View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 5 p. 1093 - 1102,970 - 979
反应条件
1: 58 percent / 0.5 h / 190 °C 2: 1.) NaH / 1.) dioxane, 90 deg C, 1 h, 2.) 125 deg C, 5 h 3: 80 percent / KOH / aq. ethanol / 3 h / Heating View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 14, # 11 p. 776 - 780
Khimiko-Farmatsevticheskii Zhurnal, , vol. 14, # 11 p. 43 - 48
反应条件
1: 89.6 percent / 10percent aq. KOH / 5 h / Heating 2: 58 percent / 0.5 h / 190 °C 3: 1.) NaH / 1.) dioxane, 90 deg C, 1 h, 2.) 125 deg C, 5 h 4: 80 percent / KOH / aq. ethanol / 3 h / Heating View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 14, # 11 p. 776 - 780
Khimiko-Farmatsevticheskii Zhurnal, , vol. 14, # 11 p. 43 - 48
反应条件
1: 61 percent / 0.5 h / 150 - 160 °C 2: 99 percent / H2O View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 5 p. 1093 - 1102,970 - 979
反应条件
1: 99 percent / 3 h / Heating 2: 61 percent / 0.5 h / 150 - 160 °C 3: 99 percent / H2O View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 5 p. 1093 - 1102,970 - 979
