1: H2 / Raney-Ni W2 / methanol / 3 h / 20 °C / atmospheric pressure 2: pyridine / 1 h / 20 °C 3: 91 percent / NaH / tetrahydrofuran / 2 h / 20 °C 4: 85 percent / i-Pr2NEt / CH2Cl2 / 2 h / 0 °C 5: 85 percent / K3PO4*3H2O; Pd(PPh3)4 / dioxane / 1.5 h / 80 °C 6: 38 percent / H2SO4 / 0.17 h / 0 °C View Scheme

1: H2 / Raney-Ni W2 / methanol / 3 h / 20 °C / atmospheric pressure 2: pyridine / 1 h / 20 °C 3: 91 percent / NaH / tetrahydrofuran / 2 h / 20 °C 4: 85 percent / i-Pr2NEt / CH2Cl2 / 2 h / 0 °C 5: 89 percent / K3PO4; PPh3; Pd(dba)2 / dioxane / 3 h / 80 °C 6: 49 percent / H2SO4 / 0.33 h / 0 °C View Scheme