2,5-双-苄氧基苯甲酸合成路线 （共 11 条）
参考文献
Gust, Devens; Moore, Thomas A.; Liddell, Paul A.; Nemeth, Gregory A.; Makings, Lewis R.; et al.
Journal of the American Chemical Society, 1987 , vol. 109, # 3 p. 846 - 856
反应条件
1: thionyl chloride 3: palladium; hot ethanol / Hydrogenation View Scheme
参考文献
Morris
Journal of the American Chemical Society, 1949 , vol. 71, p. 2056
反应条件
sodium hydroxide in 1,4-dioxane; methanol; water
14 h; Reflux;
参考文献
Thapa, Mahendra; Kim, Yunjeong; Desper, John; Chang, Kyeong-Ok; Hua, Duy H.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 353 - 356
反应条件
1: K2CO3*1.5H2O / acetone / 24 h / Heating
2: 1.99 g / NaOH / methanol; H2O / 3 h / Heating
View Scheme
参考文献
Gardner, Richard Andrew; Kinkade, Rebecca; Wang, Chaojie; Phanstiel IV, Otto
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3530 - 3537
反应条件
1: K2CO3*1.5H2O / acetone / 24 h / Heating
2: 1.99 g / NaOH / methanol; H2O / 3 h / Heating
View Scheme
参考文献
Gardner, Richard Andrew; Kinkade, Rebecca; Wang, Chaojie; Phanstiel IV, Otto
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3530 - 3537
反应条件
sodium hydroxide in 1,4-dioxane
Heating;
参考文献
Astles; Brown; Handscombe; Harper; Harris; Lewis; Lockey; McCarthy; McLay; Porter; Roach; Smith; Walsh
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 5 p. 409 - 423
反应条件
1: NaH / dimethylformamide / 100 °C
2: NaOH / dioxane / Heating
View Scheme
参考文献
Astles; Brown; Handscombe; Harper; Harris; Lewis; Lockey; McCarthy; McLay; Porter; Roach; Smith; Walsh
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 5 p. 409 - 423
反应条件
1: potassium carbonate / butan-2-one / 16 h / Heating
2: aq. NaOH / ethanol / Heating
View Scheme
参考文献
Hill, Robert A.; Carter, Rachel H.; Staunton, James
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2570 - 2576
反应条件
1: 80 percent / LiAlH4 / tetrahydrofuran / Heating
2: 90 percent / thionyl chloride, pyridine / diethyl ether
View Scheme
参考文献
Hill, Robert A.; Carter, Rachel H.; Staunton, James
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2570 - 2576
反应条件
1: 80 percent / LiAlH4 / tetrahydrofuran / Heating
2: 90 percent / thionyl chloride, pyridine / diethyl ether
3: 65 percent / Heating
4: 75 percent / aq. NaOH / ethanol / Heating
View Scheme
参考文献
Hill, Robert A.; Carter, Rachel H.; Staunton, James
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2570 - 2576
