N-(3-羟基丙基)硬脂酰胺合成路线 （共 3 条）
反应条件
1: octadecanoic acid With triethylamine; methyl chloroformate in dichloromethane
T=20°C; 2 h; Cooling with ice;
2: 3-amino-propan-1-ol in dichloromethane
T=20°C;
参考文献
Guan, Li-Ping; Sui, Xin; Deng, Xian-Qing; Zhao, Dong-Hai; Qu, You-Le; Quan, Zhe-Shan
Medicinal Chemistry Research, 2011 , vol. 20, # 5 p. 601 - 606
反应条件
sodium methylate in anhydrous xylene
参考文献
Uniroyal, Inc.
Patent: US4305868 A1, 1981 ;
反应条件
pyridine in N,N-dimethyl-formamide
24 h; Ambient temperature;
参考文献
Morris-Natschke, Susan L.; Gumus, Fatma; Marasco, Canio J.; Meyer, Karen L.; Marx, Michael; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 14 p. 2018 - 2025
