3-(3-甲氧基-4-甲基苯基)丙酸合成路线 （共 8 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=3102.9 Torr; 6 h;
参考文献
Johnson; Frescas; Oberlender; Nichols
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1662 - 1668
反应条件
sodium hydroxide in 1,4-dioxane; methanol; water
参考文献
Warner-Lambert Company
Patent: US6133303 A1, 2000 ;
US 6133303 A
反应条件
1: 99.7 percent / piperidine, piridine / 5 h / Heating
2: 99.7 percent / H2 / 10percent Pd-C / aq. ethanol / 6 h / 3102.9 Torr
View Scheme
参考文献
Johnson; Frescas; Oberlender; Nichols
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1662 - 1668
反应条件
1: pyridine; piperidine
2: platinum; ethanol / Hydrogenation
3: aqueous hydrochloric acid; boric acid; sodium carbonate / Diazotization
4: aqueous alkaline solution
View Scheme
参考文献
Fieser; Lothrop
Journal of the American Chemical Society, 1936 , vol. 58, p. 2050,2054
反应条件
1: platinum; ethanol / Hydrogenation
2: aqueous hydrochloric acid; boric acid; sodium carbonate / Diazotization
3: aqueous alkaline solution
View Scheme
参考文献
Fieser; Lothrop
Journal of the American Chemical Society, 1936 , vol. 58, p. 2050,2054
反应条件
1: aqueous hydrochloric acid; boric acid; sodium carbonate / Diazotization
2: aqueous alkaline solution
View Scheme
参考文献
Fieser; Lothrop
Journal of the American Chemical Society, 1936 , vol. 58, p. 2050,2054
反应条件
1: concentrated sulfuric acid; concentrated nitric acid / 0 - 3 °C
2: pyridine; piperidine
3: platinum; ethanol / Hydrogenation
4: aqueous hydrochloric acid; boric acid; sodium carbonate / Diazotization
5: aqueous alkaline solution
View Scheme
参考文献
Fieser; Lothrop
Journal of the American Chemical Society, 1936 , vol. 58, p. 2050,2054
参考文献
Fieser; Lothrop
Journal of the American Chemical Society, 1936 , vol. 58, p. 2050,2054
