2-羟基-5-甲氧基苯甲醛合成路线 （共 150 条）
参考文献
Mali, R. S.; Yeola, Suresh N.; Kulkarni, B. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 4 p. 352 - 354
反应条件
piperidine; propionic acid anhydride
参考文献
Cingolani et al.
Gazzetta Chimica Italiana, 1953 , vol. 83, p. 647,651
反应条件
methanol; sodium hydroxide
Verdunsten zur Trockne und lassen des Rueckstandes mit 1.5 Tln. Essigsaeureanhydrid und absol.Aether 4-5 Stdn. stehen;
参考文献
Ligand Pharmaceuticals Incorporated; The Regents of the University of California
Patent: US5808139 A1, 1998 ;
参考文献
Li, Xin; Xue, Jijun; Huang, Chusheng; Li, Ying
Chemistry - An Asian Journal, 2012 , vol. 7, # 5 p. 903 - 906
反应条件
iodine
T=85 - 90°C; 0.25 h;
参考文献
Ahmed, Naseem; van Lier, Johan E.
Tetrahedron Letters, 2006 , vol. 47, # 30 p. 5345 - 5349
反应条件
piperidine in diethyl ether
T=0 - 20°C; Knoevenagel Condensation; 2 h;
参考文献
Bag, Seema; Ghosh, Sanjukta; Tulsan, Rekha; Sood, Abha; Zhou, Weihong; Schifone, Christine; Foster, Michelle; Levine III, Harry; Toeroek, Bela; Toeroek, Marianna
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2614 - 2618
参考文献
Verma, Sanny; Kumar, Subodh; Jain, Suman L.; Sain, Bir
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 6943 - 6948
反应条件
1: NaBH4
2: polymer-supported (diacetoxyiodo)benzene / CH2Cl2 / 4 h / Ambient temperature
View Scheme
参考文献
Ley, Steven V.; Thomas, Andrew W.; Finch, Harry
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 6 p. 669 - 671
反应条件
Amberlite IRA 900 resin in 1,4-dioxane
T=85°C; 8 h;
参考文献
Mhiri; Ladhar; El Gharbi; Le Bigot
Synthetic Communications, 1999 , vol. 29, # 9 p. 1451 - 1461
反应条件
(5aS,10bR)-5a,10b-dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride; triethylamine in ethyl acetate
T=80°C; 4 h; Inert atmosphereMolecular sieve;
参考文献
Jiang, Yuansong; Chen, Wanzhi; Lu, Weimin
Tetrahedron, 2013 , vol. 69, # 18 p. 3669 - 3676
