2-羟基-5-甲氧基苯甲醛合成路线 （共 150 条）
反应条件
1: Py 2: (i) HC(OEt)3, H3PO4, (ii) /BRN= 605351/, ZnCl2, AcOEt, (iii) aq. NaOAc, AcOH 3: NaOMe / methanol View Scheme
参考文献
Billman; Tonnis
Journal of pharmaceutical sciences, 1971 , vol. 60, # 8 p. 1188 - 1192
反应条件
in benzene T=110°C; Wittig olefination; 7 h; Inert atmosphere;
参考文献
Zeitler, Kirsten; Rose, Christopher A.
Journal of Organic Chemistry, 2009 , vol. 74, # 4 p. 1759 - 1762
反应条件
in tetrahydrofuran; ethanol T=80°C; 24 h;
参考文献
Otsubo, Tadamune; Minami, Akira; Fujii, Haruna; Taguchi, Risa; Takahashi, Tadanobu; Suzuki, Takashi; Teraoka, Fumiteru; Ikeda, Kiyoshi
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 7 p. 2245 - 2249
反应条件
1: With potassium phosphate in ethanol T=20°C; 1 h; 2: With ammonium chloride in ethanol
参考文献
Undale, Kedar A.; Gaikwad, Dipak S.; Shaikh, Tarannum S.; Desai, Uday V.; Pore, Dattaprasad M.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 7 p. 1039 - 1042
反应条件
Montmorillonite KSF in water T=100°C; Knoevenagel condensation; 24 h;
参考文献
Heravi, Majid M.; Hekmatshoar, Rahim; Emamgholizadeh, Maryam
Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 9 p. 1893 - 1896
反应条件
piperidine; trifluoroacetic acid 1.) pyridine, RT, 16 h; 2.) CH2Cl2, 1 h;
参考文献
Watson, Brett T.; Christiansen, Gerda E.
Tetrahedron Letters, 1998 , vol. 39, # 33 p. 6087 - 6090
反应条件
1-butylpyridinium bromide T=100°C; Microwave irradiationNeat (no solvent);
参考文献
Passiniemi, Mikko; Myllymaeki, Mikko J.; Vuokko, Juha; Koskinen, Ari M.P.
Letters in Organic Chemistry, 2011 , vol. 8, # 1 p. 48 - 52
反应条件
9,10-dihydro-anthracene T=526.84°C; P=5E-05 Torr; Activation energy; Further Variations:Temperatures;
参考文献
Pratt; De Heer; Mulder; Ingold
Journal of the American Chemical Society, 2001 , vol. 123, # 23 p. 5518 - 5526
参考文献
Tiemann; Mueller
Chemische Berichte, 1881 , vol. 14, p. 1986
反应条件
1.1: 41 percent / K2CO3 / dimethylformamide / 20 - 80 °C 2.1: BBr3 / CH2Cl2 / -15 - 20 °C 2.2: 76 percent / SOCl2 / methanol / 20 - 70 °C View Scheme
参考文献
Martin; Winkler
Helvetica Chimica Acta, 1994 , vol. 77, # 1 p. 100 - 110
