4-甲氧基-6-甲基-2H-吡喃酮合成路线 （共 57 条）
反应条件
1: 3-Bromo-4-methoxy-6-methyl-2-pyranone With palladium diacetate; sodium carbonate; triphenylphosphine in benzene 0.5 h; 2: benzaldehyde-4-boronic acid in ethanol; benzene Suzuki cross-coupling; 6 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 16 p. 2667 - 2671
参考文献
Hansen, Chad A.; Frost
Journal of the American Chemical Society, 2002 , vol. 124, # 21 p. 5926 - 5927
反应条件
1: 3-Bromo-4-methoxy-6-methyl-2-pyranone With palladium diacetate; sodium carbonate; triphenylphosphine in benzene 0.5 h; 2: 3-nitro-phenyl boronic acid in ethanol; benzene Suzuki cross-coupling; 6 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 16 p. 2667 - 2671
反应条件
1: 2) aq. KOH / 2) Et3NCH2PhCl / 1) Et2O, -19 deg C, 2 h, 2) Et2O, r.t., 4 h 2: 96 percent / Na2CO3 / acetone / Heating View Scheme
参考文献
Chemische Berichte, , vol. 117, # 11 p. 3270 - 3279
反应条件
1: 2) aq. KOH / 2) Et3NCH2PhCl / 1) Et2O, -19 deg C, 2 h, 2) Et2O, r.t., 4 h 2: 96 percent / Na2CO3 / acetone / Heating View Scheme
参考文献
Chemische Berichte, , vol. 117, # 11 p. 3270 - 3279
反应条件
1: sulfuric acid / 0.25 h / 130 °C / Cooling with ice 2: potassium carbonate / acetone / Inert atmosphere; Reflux View Scheme
参考文献
European Journal of Organic Chemistry, , # 19 p. 3607 - 3616
反应条件
1: 60 percent / H2SO4; H2O / 1.5 h / 120 °C 2: 99 percent / K2CO3 / various solvent(s) / 8 h / Heating View Scheme
参考文献
Cell Biology and Toxicology, , vol. 13, # 3 p. 141 - 153
反应条件
hydrogenchloride; methanol
参考文献
Roczniki Chemii, , vol. 27, p. 456,464
Chem.Abstr., , p. 3176
反应条件
n-butyllithium; dimethyl sulfate 1.) THF, HMPT, -78 deg C, 2.) 5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Synthetic Communications, , vol. 14, # 6 p. 521 - 532
反应条件
n-butyllithium 1.) THF, HMPT, -78 deg C, 2.) 5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Synthetic Communications, , vol. 14, # 6 p. 521 - 532
