4-甲氧基-6-甲基-2H-吡喃酮合成路线 （共 57 条）
反应条件
n-butyllithium in hexane
T=-78°C; 3 h;
参考文献
Carpenter, T. Adrian; Evans, Geoffrey E.; Leeper, Finian J.; Staunton, James; Wilkinson, Michael R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 5 p. 1043 - 1051
反应条件
5 Pd/Al2O3; hydrogen in isopropyl alcohol
T=20°C; P=1500.15 Torr;
参考文献
Schmidt, Erik; Bucher, Christoph; Santarossa, Gianluca; Mallat, Tamas; Gilmour, Ryan; Baiker, Alfons
Journal of Catalysis, 2012 , vol. 289, p. 238 - 248
反应条件
N-bromosuccinmide in tetrachloromethane
Bromination; 1 h; Heating;
参考文献
Lokot; Pashkovskii; Lakhvich
Russian Journal of Organic Chemistry, 1998 , vol. 34, # 9 p. 1350 - 1354
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
2 h; HeatingIrradiation;
参考文献
Bacardit, R.; Moreno-Manas, M.; Pleixats, R.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 157 - 160
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
2 h; HeatingIrradiation;
参考文献
March, P. de; Moreno-Manas, M.; Pi, R.; Ripoll, I.; Sanchez-Fernando, F.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1537 - 1542
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
20 h; Heating;
参考文献
Shimo, Tetsuro; Ohe, Masayuki; Somekawa, Kenichi; Tsuge, Otohiko
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 1831 - 1833
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
2 h; HeatingIrradiationother solvent (benzene), reaction time, temperature, AIBN; Product distribution;
参考文献
Bacardit, R.; Moreno-Manas, M.; Pleixats, R.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 157 - 160
反应条件
diphosphorus pentasulfide; benzene
参考文献
Arndt; Avan
Chemische Berichte, 1951 , vol. 84, p. 343,347
反应条件
1: selenium(IV) oxide / 1,4-dioxane / 5 h / 180 °C / Inert atmosphere; Sealed tube
2: n-butyllithium; triphenyl-methyl-phosphonium iodide / tetrahydrofuran / 3 h / -78 - 20 °C / Inert atmosphere
3: sodium acetate; palladium diacetate / acetonitrile / 0.17 h
4: 5 Pd(II)/C(eggshell); hydrogen / methanol / 1.5 h / 20 °C
View Scheme
参考文献
Soldi, Cristian; Moro, Angelica V.; Pizzolatti, Moacir G.; Correia, Carlos R. D.
European Journal of Organic Chemistry, 2012 , # 19 p. 3607 - 3616
反应条件
methanol; magnesium
6 h; Inert atmosphereReflux;
参考文献
McCracken, Stephen T.; Kaiser, Marcel; Boshoff, Helena I.; Boyd, Peter D.W.; Copp, Brent R.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 4 p. 1482 - 1493
