4-(4-甲氧基苯基)哌啶合成路线 （共 8 条）
反应条件
5 palladium on charcoal; hydrogen in methanol T=20°C; P=2947.82 Torr; 24 h;
参考文献
Arnatt, Christopher K.; Zaidi, Saheem A.; Zhang, Zhu; Li, Guo; Richardson, Amanda C.; Ware, Joy L.; Zhang, Yan
European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 647 - 658
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; Hydrogenolysis;
参考文献
Eastwood, Paul R.
Tetrahedron Letters, 2000 , vol. 41, # 19 p. 3705 - 3708
反应条件
palladium in ethanol
反应条件
ammonium hydroxide in methanol; dichloromethane
反应条件
1: 73 percent / K2CO3; PdCl2dppf / dimethylformamide / 80 °C 2: 99 percent / H2 / Pd/C / ethanol / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 19 p. 3705 - 3708
反应条件
1: 85 percent / PdCl2dppf; dppf; KOAc / dioxane / 80 °C 2: 73 percent / K2CO3; PdCl2dppf / dimethylformamide / 80 °C 3: 99 percent / H2 / Pd/C / ethanol / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 19 p. 3705 - 3708
反应条件
1: 73 percent / K2CO3; PdCl2dppf / dimethylformamide / 80 °C 2: 99 percent / H2 / Pd/C / ethanol / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 19 p. 3705 - 3708
反应条件
1.1: magnesium; iodine / tetrahydrofuran / 1 h / |Reflux 1.2: 0.83 h / 20 °C / |Reflux 1.3: 3 h / |Reflux 2.1: 5 palladium on charcoal; hydrogen / methanol / 24 h / 20 °C / 2947.82 Torr View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 69, p. 647 - 658
