hydrogen; palladium 10 on activated carbon in methanol P=2327.23 Torr; 2 h;

1: With hydrogen; trifluoroacetic acid; 5 Pd(II)/C(eggshell) in methanol T=30°C; 2: With sodium hydroxide in water pH=8 - 9;

1.1: sodium t-butanolate / 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; tris-(dibenzylideneacetone)dipalladium(0) / toluene / 100 °C 2.1: trifluoroacetic acid / dichloromethane / 2 h / 30 °C 2.2: pH 7 - 8 3.1: potassium phosphate / tri-cyclo-hexyl-phosphine; tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane / 100 °C / Inert atmosphere; Sealed tube 4.1: hydrogen; trifluoroacetic acid / 5 Pd(II)/C(eggshell) / methanol / 30 °C 4.2: pH 8 - 9 View Scheme

1.1: potassium phosphate / tri-cyclo-hexyl-phosphine; tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane / 100 °C / Inert atmosphere; Sealed tube 2.1: hydrogen; trifluoroacetic acid / 5 Pd(II)/C(eggshell) / methanol / 30 °C 2.2: pH 8 - 9 View Scheme