乙基2,5-二氢-5-氧代-1-苯基-1H-1,2,4-噻唑-3-羧酸合成路线 （共 2 条）
反应条件
1: 2,4(3H,5H)-Thiazoledione With potassium hydroxide in ethanol
1 h; Reflux;
2: oxalyl chloride phenylhydrazone ethyl ester in ethanol
1.5 h; Reflux;
参考文献
Matiychuk, Vasyl S.; Potopnyk, Mykhaylo A.; Luboradzki, Roman; Obushak, Mykola D.
Synthesis, 2011 , # 11 p. 1799 - 1803
反应条件
1.1: hydrogenchloride; sodium nitrite / water / 0 °C
1.2: 4 h / 0 °C
2.1: potassium hydroxide / ethanol / 1 h / Reflux
2.2: 1.5 h / Reflux
View Scheme
参考文献
Matiychuk, Vasyl S.; Potopnyk, Mykhaylo A.; Luboradzki, Roman; Obushak, Mykola D.
Synthesis, 2011 , # 11 p. 1799 - 1803
