1: PTAS With tetrabutyl ammonium fluoride in tetrahydrofuran; water T=20°C; 1 h; 2: 1-Chloro-3,4-difluoro-benzene With 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; bis(η3-allyl-μ-chloropalladium(II)) in tetrahydrofuran; water T=80°C; 3 h;

sodium carbonate in ethanol; water T=80°C; Suzuki-Miyaura coupling; 4 h;

1.1: 91 percent / diethyl ether / 12 h / Heating 2.1: tetrabutylammonium fluoride trihydrate / tetrahydrofuran; H2O / 1 h / 20 °C 2.2: 89 percent / 2-dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl / [(η3-C3H5)PdCl]2 / tetrahydrofuran; H2O / 3 h / 80 °C View Scheme

iron(III) benzoate T=80°C; 72 h;

trichloroacetic acid T=80°C; 72 h; other reagent, without reagent; Product distribution;