1: 100 percent / SOCl2 2: 89 percent / tetrahydrofuran / 1 h / 0 °C 3: 98 percent / LiCl, NaBH4 / ethanol / 17 h / Ambient temperature 4: 81 percent / SO3*Py, Et3N / toluene; dimethylsulfoxide / 0.33 h / Ambient temperature 5: 100 percent / benzyltributylammonium chloride / CH2Cl2; H2O / 3 h / 0 °C 6: 50 percent / aq. HCl / ethyl acetate / 14 h / 80 - 100 °C View Scheme
参考文献
Matsuda, Fuyuhiko; Mtsumoto, Teruyo; Ohsaki, Masako; Ito, Yoshio; Terashima, Shiro
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 2 p. 360 - 365
1: D-(+)-Phenylalanine With lithium aluminium tetrahydride in tetrahydrofuran 6 h; HeatingReflux; 2: With water; sodium hydroxide in tetrahydrofuran T=0 - 20°C; 0.5 h; 3: di-tert-butyl dicarbonate in tetrahydrofuran; dichloromethane; water
参考文献
IMTM GMBH; ANSORGE, Siegfried; BANK, Ute; NORDHOFF, Karsten; ROeHNERT, Peter; STEFIN, Sofia; STRIGGOW, Frank; TAeGER, Michael
Patent: WO2011/26781 A1, 2011 ;
Location in patent: Page/Page column 77-78 ;
WO 2011/026781 A1
