1,3,5-三羟基-9H-氧杂蒽-9-酮合成路线 （共 14 条）
反应条件
1: With potassium hydroxide in water T=10°C; 48 h; 2: With hydrogenchloride in water regioselective reaction;
参考文献
Zhang, Xiaojin; Li, Xiang; Tao, Lei; Gao, Yuan; Gong, Dandan; Xi, Meiyang; Xu, Xiaoli; Guo, Qinglong; You, Qidong; Ye, Suofu; Zhang, Yu; Meng, Huyan; Zhang, Mingqian; Gao, Wenlei
Medicinal Chemistry, 2012 , vol. 8, # 6 p. 1012 - 1025,14
反应条件
potassium hydroxide T=20°C; 16 h;
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
反应条件
tin(ll) chloride
T=140°C; 0.0138889 h; Microwave irradiation; regioselective reaction;
参考文献
Verbanac, Donatella; Jain, Subhash C.; Jain, Nidhi; Chand, Mahesh; Cipcic Paljetak, Hana; Matijasic, Mario; Peric, Mihaela; Stepanic, Visnja; Saso, Luciano
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 10 p. 3180 - 3185
反应条件
boron tribromide in dichloromethane
T=20°C; 24 h;
参考文献
Genoux-Bastide, Estelle; Lorendeau, Doriane; Nicolle, Edwige; Yahiaoui, Samir; Magnard, Sandrine; DiPietro, Attilio; Baubichon-Cortay, Helene; Boumendjel, Ahcene
ChemMedChem, 2011 , vol. 6, # 8 p. 1478 - 1484
反应条件
hydrogen iodide; phenol
24 h; Heating;
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
参考文献
National Science Council
Patent: US5741813 A1, 1998 ;
反应条件
1: oxalyl chloride / CH2Cl2 / 3 h / 20 °C
2: 86 percent / AlCl3 / CH2Cl2 / 15 h / 20 °C
3: 93 percent / pyridine; aq. tetramethylammonium hydroxide / 4 h / Heating
4: 95 percent / aq. HI; phenol / 24 h / Heating
View Scheme
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
反应条件
1: 86 percent / AlCl3 / CH2Cl2 / 15 h / 20 °C
2: 93 percent / pyridine; aq. tetramethylammonium hydroxide / 4 h / Heating
3: 95 percent / aq. HI; phenol / 24 h / Heating
View Scheme
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
反应条件
1: methanesulfonic acid; phosphorous pentoxide / 0.25 h / 100 °C
2: boron tribromide / dichloromethane / 24 h / 20 °C
View Scheme
参考文献
Genoux-Bastide, Estelle; Lorendeau, Doriane; Nicolle, Edwige; Yahiaoui, Samir; Magnard, Sandrine; DiPietro, Attilio; Baubichon-Cortay, Helene; Boumendjel, Ahcene
ChemMedChem, 2011 , vol. 6, # 8 p. 1478 - 1484
反应条件
1: 93 percent / pyridine; aq. tetramethylammonium hydroxide / 4 h / Heating
2: 95 percent / aq. HI; phenol / 24 h / Heating
View Scheme
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
