N-Boc-DL-苯甘氨醇合成路线 （共 46 条）
反应条件
2,4,6-trimethyl-pyridine; trifluoroacetic anhydride in acetonitrile T=0°C; Pummerer reaction; 0.25 h;
参考文献
Journal of Organic Chemistry, , vol. 65, # 10 p. 2856 - 2862
反应条件
1: Et3N / acetonitrile; H2O / 1 h / 0 °C 2: 96 percent / H2 / Pd(OH)2/C / methanol / 1 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 52 p. 9691 - 9693
反应条件
sodium tetrahydroborate in methanol T=0°C; 0.5 h; Title compound not separated from byproducts;
参考文献
Synthesis, , # 2 p. 181 - 186
反应条件
1: (-)-(2R)-2-phenylglycine With lithium aluminium tetrahydride 2: di-tert-butyl dicarbonate
参考文献
Liang, Ningning; Srinivas, Pusuluri; Datta, Apurba
Tetrahedron Letters, 2005 , vol. 46, # 42 p. 7221 - 7223
反应条件
sodium hydroxide; (DHQD)2PHAL; potassium dioxotetrahydroxoosmate(VI); tert-butylhypochlorite 1.) n-PrOH, H2O, 5 min, 2.) n-PrOH, H2O, 0 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 16 p. 2519 - 2526
反应条件
1: 98 percent / i-Pr2NH; BuLi / tetrahydrofuran; hexane / 0.25 h / -78 °C 2: 95 percent / TFA / methanol / 15 h / 20 °C 3: 91 percent / Et3N / acetonitrile / 15 h / 20 °C 4: sym-collidine; TFAA / acetonitrile / 0.25 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 10 p. 2856 - 2862
反应条件
1: 91 percent / Et3N / acetonitrile / 15 h / 20 °C 2: sym-collidine; TFAA / acetonitrile / 0.25 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 10 p. 2856 - 2862
反应条件
1: 95 percent / TFA / methanol / 15 h / 20 °C 2: 91 percent / Et3N / acetonitrile / 15 h / 20 °C 3: sym-collidine; TFAA / acetonitrile / 0.25 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 10 p. 2856 - 2862
反应条件
lithium borohydride in ethanol Yield given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1479 - 1481
