1-氧代-1,2,3,4-四氢萘-2-羧酸乙酯合成路线 （共 33 条）
反应条件
1: Na / ethanol
2: Na / toluene
3: P2S5 / pyridine
4: (i) (irradiation), benzene, (ii) Hg(OAc)2, AcOH
View Scheme
参考文献
Couture,A. et al.
Journal of the American Chemical Society, 1976 , vol. 98, p. 6218 - 6225
反应条件
1: 1.) MeONa / 1.) MeOH, room temp., 90 min, 2a.) MeOH, 18 h, 2b.) reflux, 3 h
2: 89 percent / 48percent aq. HBr/HBr(gas) / propionic acid / 4 h / Heating
3: 12.6 g / 2 h / 110 °C
4: 1.) BuLi / tetrahydrofuran / 1.) RT, 1 h, 2.) reflux, 5 h
View Scheme
参考文献
Chini, Marco; Crotti, Paolo; Macchia, Franco
Journal of Organic Chemistry, 1989 , vol. 54, # 16 p. 3930 - 3936
参考文献
Hueckel; Goth
Chemische Berichte, 1924 , vol. 57, p. 1290
