4-[二(2-氯乙基)氨基]氢化肉桂酸合成路线 （共 6 条）
反应条件
hydrogenchloride
T=100°C; 4 h;
参考文献
Khunnawutmanotham, Nisachon; Chimnoi, Nitirat; Champathong, Wattanachai; Lerdsirisuk, Pradit; Khotmor, Theeraphon; Techasakul, Supanna
Journal of Chemical Research, 2012 , vol. 36, # 6 p. 374 - 378
反应条件
1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 1.5 h / 20 °C
2: hydrogenchloride / 4 h / 100 °C
View Scheme
参考文献
Khunnawutmanotham, Nisachon; Chimnoi, Nitirat; Champathong, Wattanachai; Lerdsirisuk, Pradit; Khotmor, Theeraphon; Techasakul, Supanna
Journal of Chemical Research, 2012 , vol. 36, # 6 p. 374 - 378
反应条件
1.1: trichlorophosphate / 1,2-dichloro-ethane / 0.17 h / 0 °C
1.2: 3 h / Reflux
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere
2.2: 1.5 h / 20 °C / Inert atmosphere
3.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 1.5 h / 20 °C
4.1: hydrogenchloride / 4 h / 100 °C
View Scheme
参考文献
Khunnawutmanotham, Nisachon; Chimnoi, Nitirat; Champathong, Wattanachai; Lerdsirisuk, Pradit; Khotmor, Theeraphon; Techasakul, Supanna
Journal of Chemical Research, 2012 , vol. 36, # 6 p. 374 - 378
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere
1.2: 1.5 h / 20 °C / Inert atmosphere
2.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 1.5 h / 20 °C
3.1: hydrogenchloride / 4 h / 100 °C
View Scheme
参考文献
Khunnawutmanotham, Nisachon; Chimnoi, Nitirat; Champathong, Wattanachai; Lerdsirisuk, Pradit; Khotmor, Theeraphon; Techasakul, Supanna
Journal of Chemical Research, 2012 , vol. 36, # 6 p. 374 - 378
反应条件
1: 150 °C
2: benzene; POCl3
3: aqueous HCl
View Scheme
参考文献
Everett et al.
Journal of the Chemical Society, 1953 , p. 2386,2387
反应条件
1: benzene; POCl3
2: aqueous HCl
View Scheme
参考文献
Everett et al.
Journal of the Chemical Society, 1953 , p. 2386,2387
