4-羟基-6-甲基-2-吡喃酮合成路线 （共 149 条）
反应条件
sulfuric acid T=130°C; 0.25 h;
参考文献
Nagawade, Rahul R.; Khanna, Vijay V.; Bhagwat, Sachin S.; Shinde, Devanand B.
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 12 p. 1325 - 1330
反应条件
type III polyketide synthase RppA from S. griseus; 2-hydroxyethanethiol in various solvent(s) T=37°C; pH=7.5; 2 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 1 p. 64 - 65
参考文献
Toray Industries, Inc.
Patent: US6215016 B1, 2001 ;
反应条件
in sulfuric acid; water T=120°C; Deacetylation; 1.5 h;
参考文献
Gonindard; Bergonzi; Denier; Sergheraert; Klaebe; Chavant; Hollande
Cell Biology and Toxicology, 1997 , vol. 13, # 3 p. 141 - 153
反应条件
calicheamicin polyketide synthase CalE8; calicheamicin thioesterase CalE7; NADPH in glycerol T=24°C; pH=7; 2 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Journal of the American Chemical Society, , vol. 131, # 35 p. 12564 - 12566
反应条件
1: With recombinant CazF expressed from S. cerevisiae BJ5464-NpgA2 in aq. phosphate buffer T=20°C; Claisen Condensation; pH=7.4; 1 h; Enzymatic reaction; 2: With sodium hydroxide in water T=65°C; 0.166667 h;
参考文献
Organic Letters, , vol. 15, # 14 p. 3774 - 3777
反应条件
trifluoroacetic acid; trifluoroacetic anhydride 0.5 h; Heating;
参考文献
Evans, Geoffrey E.; Staunton, James
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 755 - 762
反应条件
in toluene 0.166667 h; Heating;
参考文献
Sato, Masayuki; Sakaki, Jun-ichi; Sugita, Yoshiaki; Yasuda, Sanae; Sakoda, Hiroko; Kaneko, Chikara
Tetrahedron, 1991 , vol. 47, # 30 p. 5689 - 5708
反应条件
in 1,4-dioxane 2 h; Heating;
参考文献
Haeusler, Johannes
Monatshefte fuer Chemie, 1982 , vol. 113, p. 1213 - 1216
参考文献
Lokot, Igor P.; Pashkovsky, Felix S.; Lakhvich, Fedor A.
Tetrahedron, 1999 , vol. 55, # 15 p. 4783 - 4792
