4-羟基-6-甲基-2-吡喃酮合成路线 （共 149 条）
反应条件
trifluoroacetic acid
参考文献
Groutas, William C.; Stanga, Michael A.; Brubaker, Michael J.; Huang, Tien L.; Moi, Min K.; Carroll, Robert T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1106 - 1109
反应条件
Amberlyst.(R). 70 in water T=100°C; P=22502.3 Torr; 4 h; Inert atmosphere; Product distribution / selectivity;
参考文献
US2012/283477 A1, ;
Page/Page column 3-4 ;
反应条件
1: potassium carbonate / acetone / Inert atmosphere; Reflux 2: selenium(IV) oxide / 1,4-dioxane / 5 h / 180 °C / Inert atmosphere; Sealed tube 3: n-butyllithium; triphenyl-methyl-phosphonium iodide / tetrahydrofuran / 3 h / -78 - 20 °C / Inert atmosphere 4: sodium acetate; palladium diacetate / acetonitrile / 0.17 h View Scheme
参考文献
Soldi, Cristian; Moro, Angelica V.; Pizzolatti, Moacir G.; Correia, Carlos R. D.
European Journal of Organic Chemistry, 2012 , # 19 p. 3607 - 3616
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in dichloromethane 2 h; HeatingIrradiation;
参考文献
March, P. de; Moreno-Manas, M.; Pi, R.; Ripoll, I.; Sanchez-Fernando, F.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1537 - 1542
反应条件
trifluoroacetic acid 3 h; Heating;
参考文献
Groutas, William C.; Stanga, Michael A.; Brubaker, Michael J.; Huang, Tien L.; Moi, Min K.; Carroll, Robert T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1106 - 1109
反应条件
hydrogen; 5 Pd/Nb2O5 in isopropyl alcohol T=49.84°C; P=5171.62 Torr; 5 h; Product distribution / selectivity;
参考文献
US2012/116119 A1, ;
Page/Page column 5 ;
反应条件
hydrogen; platinum in ethyl acetate P=760 Torr; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 21, p. 551 - 554
反应条件
hydrogen; 5 Pd/Nb2O5 in butan-1-ol T=69.84°C; P=5171.62 Torr; 5 h;
参考文献
US2012/116119 A1, ;
Page/Page column 5 ;
反应条件
hydrogen; 5 Pd/Nb2O5 in isopropyl alcohol T=49.84°C; P=5171.62 Torr; 5 h; Product distribution / selectivity;
参考文献
US2012/116119 A1, ;
Page/Page column 5 ;
反应条件
palladium 10 on activated carbon in tetrahydrofuran T=49.84°C; P=25858.1 Torr; 8 h;
参考文献
US2012/116119 A1, ;
Page/Page column 6 ;
