(2,2,2-三氟乙氧基)乙酸合成路线 (共 3 条)
反应条件
sodium hydroxide; sulfuric acid in methanol
参考文献
Imperial Chemical Industries PLC
Patent: US5266570 A1, 1993 ;
反应条件
1: With sodium hydroxide
T=20 - 60°C; 72 h;
2: With sulfuric acid in water
T=0°C;
参考文献
PHARMACIA and UPJOHN COMPANY LLC
Patent: WO2006/126081 A2, 2006 ;
Location in patent: Page/Page column 56 ;
反应条件
in water; toluene; mineral oil
参考文献
Chevron Research Company
Patent: US4846873 A1, 1989 ;