反应条件
1: 1.) Grignard reagent prepared from 1-trimethylsilyl-3-chloro-3-methyl-1-butyne, THF, HMPA, 0 deg C 2.) aqueous KF, DMF, 8 h, 70-80 deg C 2: SeO2, pyridine / aq. ethanol / Heating 3: 75 percent / s-collidine, LiCl, mesyl chloride / 2 h / 0 °C 4: 1.) THF, disiamylborane, -10 deg C 2.) benzene, Pd(PPh3)4, 4N-aqueous NaOH, reflux, 30 min View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 7 p. 761 - 764
