3-(苯基甲基)-3,8-二氮杂双环[3.2.1]辛烷合成路线 （共 17 条）
反应条件
LiAlH4 in diethyl ether
参考文献
PFIZER INC.
Patent: EP1213289 A1, 2002 ;
Location in patent: Page 12 ;
反应条件
1: With triethylamine in dichloromethane T=0 - 20°C; 72 h; 2: With trifluoroacetic acid in 1,2-dichloro-ethane T=20°C; 2 h;
参考文献
US2007/270405 A1, ;
Page/Page column 50 ;
US 20070270405 A1
反应条件
1: toluene / 85 °C 2: xylene / Heating 3: 230 °C 4: H2; HCl / Pd/C / H2O / 85 h / 760 Torr 5: LiAlH4 / diethyl ether / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 5 p. 899 - 902
反应条件
1: xylene / Heating 2: 230 °C 3: H2; HCl / Pd/C / H2O / 85 h / 760 Torr 4: LiAlH4 / diethyl ether / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 5 p. 899 - 902
反应条件
1: H2; HCl / Pd/C / H2O / 85 h / 760 Torr 2: LiAlH4 / diethyl ether / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 5 p. 899 - 902
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 4 p. 1084 - 1088
反应条件
1: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C 2: triethylamine / dichloromethane / 20 °C 3: acetonitrile / Reflux View Scheme
参考文献
Chinese Chemical Letters, , vol. 22, # 5 p. 523 - 526
反应条件
1: triethylamine / dichloromethane / 20 °C 2: acetonitrile / Reflux View Scheme
参考文献
Chinese Chemical Letters, , vol. 22, # 5 p. 523 - 526
反应条件
in acetonitrile Reflux;
参考文献
Chinese Chemical Letters, , vol. 22, # 5 p. 523 - 526
