3-甲氧基-4-硝基苯甲酰氯合成路线 （共 19 条）
反应条件
thionyl chloride in toluene
1 h; Heating / reflux;
参考文献
DEVELOGEN AKTIENGESELLSCHAFT
Patent: WO2007/59905 A2, 2007 ;
Location in patent: Page/Page column 42-43 ;
WO 2007/059905 A2
参考文献
Biogen, Inc.
Patent: US6239108 B1, 2001 ;
反应条件
in hexane; dichloromethane; N,N-dimethyl-formamide
参考文献
Hinks; Jeremy David; Takle; Andrew Kenneth; Hunt; Eric
Patent: US6020368 A1, 2000 ;
参考文献
American Cyanamid Company
Patent: US5733905 A1, 1998 ;
Title/Abstract Full Text Show Details
American Cyanamid Company
Patent: US5516774 A1, 1996 ;
Title/Abstract Full Text Show Details
American Cyanamid Company
Patent: US5736540 A1, 1998 ;
反应条件
1: aq. 1M NaOH / methanol / 0.5 h
2: thionyl chloride / 1 h / Heating
View Scheme
参考文献
Adams, S. R.; Kao, J. P. Y.; Tsien, R. Y.
Journal of the American Chemical Society, 1989 , vol. 111, # 20 p. 7957 - 7968
反应条件
1: KMnO4 / H2O / Heating
2: SOCl2
View Scheme
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
反应条件
2: 13 g / 85 °C / Hofmann rearrangement
View Scheme
参考文献
Shine, Henry J.; Park, Koon Ha; Brownawell, Marilyn L.; Filippo, Joseph San
Journal of the American Chemical Society, 1984 , vol. 106, # 23 p. 7077 - 7082
反应条件
triethylamine in N,N-dimethyl-formamide; toluene
T=55 - 65°C; 1 h; Product distribution / selectivity;
参考文献
Boehringer Ingelheim International GmbH
Patent: US2008/177066 A1, 2008 ;
Location in patent: Page/Page column 56-58 ;
反应条件
ammonia in tetrahydrofuran; 1,4-dioxane
T=0 - 20°C; 5 h;
参考文献
DEVELOGEN AKTIENGESELLSCHAFT
Patent: WO2007/59905 A2, 2007 ;
Location in patent: Page/Page column 43 ;
WO 2007/059905 A2
