5-溴-1-异丙基-1H-吲哚合成路线 (共 1 条)
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C 1.2: -78 - 20 °C 2.1: palladium 10 on activated carbon; potassium carbonate / water; acetonitrile / 4 h / 50 - 60 °C 3.1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 80 - 90 °C View Scheme
参考文献
Xie, Fuchun; Zhao, Hongbing; Li, Dewen; Chen, Hong; Quan, Haitian; Shi, Xiaojing; Lou, Liguang; Hu, Youhong
Journal of Medicinal Chemistry, 2011 , vol. 54, # 9 p. 3200 - 3205