1: in tetrahydrofuran T=20°C; 24 h; 2: With palladium on activated charcoal; hydrogen in tetrahydrofuran 24 h;

1: With C43H55N3O3S; (2-chlorophenyl)methylamine in benzene T=50°C; 60 h; Molecular sieveInert atmosphereSchlenk technique; 2: With hydrogenchloride in tetrahydrofuran; benzene enantioselective reaction;