6-溴咪唑并[1,2-a]吡啶-2-羧酸乙酯合成路线 （共 4 条）
反应条件
1: in ethanol 8 h; Reflux; 2: With sodium hydrogencarbonate in water
参考文献
Katoh, Issei; Aoki, Toshiaki; Suzuki, Hideyuki; Utsunomiya, Iwao; Kuroda, Norikazu; Iwaki, Tsutomu
Patent: US2011/98471 A1, 2011 ;
Location in patent: Page/Page column 57 ;
反应条件
potassium hydroxide in ethanol; water
参考文献
Warshakoon, Namal C.; Wu, Shengde; Boyer, Angelique; Kawamoto, Richard; Sheville, Justin; Renock, Sean; Xu, Kevin; Pokross, Matthew; Evdokimov, Artem G.; Walter, Richard; Mekel, Marlene
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 21 p. 5598 - 5601
反应条件
1: 66.3 percent / diisobutylaluminum hydride / CH2Cl2 / 3 h / 0 - 10 °C 2: thionyl chloride / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Yamanaka; Miyake; Suda; Ohhara; Ogawa
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 6 p. 1556 - 1567
反应条件
diisobutylaluminium hydride in dichloromethane T=0 - 10°C; 3 h;
参考文献
Yamanaka; Miyake; Suda; Ohhara; Ogawa
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 6 p. 1556 - 1567
