1: With N-bromosuccinmide; triphenylphosphine in dichloromethane T=0°C; 0.25 h; 2: 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid in dichloromethane T=0 - 25°C; 0.75 h; 3: 2-amino-thiazole in dichloromethane T=25°C; 16 h;