4-{[4-(3,4-二氯苯氧基)哌啶-1-基]甲基}哌啶-1-羧酸叔丁酯合成路线 (共 2 条)
反应条件
1: With acetic acid in tetrahydrofuran
T=20°C; 0.5 h;
2: With sodium tris(acetoxy)borohydride in tetrahydrofuran
T=20°C;
参考文献
ASTRAZENECA AB
Patent: WO2004/87659 A1, 2004 ;
Location in patent: Page 28-29 ;
WO 2004/087659 A1
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 1 h;
参考文献
ASTRAZENECA AB
Patent: WO2004/85423 A1, 2004 ;
Location in patent: Page 23 ;
WO 2004/085423 A1