N-乙酰基-2-氯-2-脱氧神经氨酸甲酯4,7,8,9-四乙酸酯合成路线 （共 51 条）
反应条件
Ag2CO3; water in acetone T=20°C; 0.5 h; Inert atmosphere;
参考文献
Wolf, Saskia; Warnecke, Svenja; Ehrit, Joerg; Freiberger, Friedrich; Gerardy-Schahn, Rita; Meier, Chris
ChemBioChem, 2012 , vol. 13, # 17 p. 2605 - 2615
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium thioacyanate in dichloromethane 0.5 h; Heating;
参考文献
Liebigs Annalen der Chemie, , # 8 p. 799 - 802
反应条件
N-benzyl-N,N,N-triethylammonium chloride in dichloromethane 0.5 h; Heating;
参考文献
Liebigs Annalen der Chemie, , # 8 p. 799 - 802
反应条件
1: 57 percent / dimethylformamide / 12 h / Ambient temperature 2: 71 percent / M sodium methoxide / methanol / 1 h / Ambient temperature View Scheme
参考文献
Carbohydrate research, , vol. 162, # 2 p. 294 - 297
反应条件
1: 60 percent / benzyltriethylammonium chloride / aq. NaOH; CHCl3 / 0.42 h / Heating View Scheme
参考文献
Rothermel; Faillard
Carbohydrate research, 1990 , vol. 208, p. 251 - 254
反应条件
1: 62 percent / triethylamine / CH2Cl2 / 1 h 2: sodium methoxide (1 M) / methanol / 1.5 h 3: NaOH (0.1 N) / methanol; H2O / 1 h View Scheme
参考文献
Baggett; Marsden
Carbohydrate research, 1982 , vol. 110, # 1 p. 11 - 18
反应条件
in acetonitrile 2 h; Title compound not separated from byproducts;
参考文献
Sabesan, Subramaniam; Neira, Susana; Davidson, Fred; Duus, Jens .; Bock, Klaus
Journal of the American Chemical Society, 1994 , vol. 116, # 5 p. 1616 - 1634
反应条件
1.1: 90 percent / CH2Cl2 / 20 h / 20 °C 2.1: Na; MeOH / 0.67 h / -40 °C 2.2: 91 percent / dimethylformamide / 20 °C View Scheme
参考文献
Harrison, Jennifer A.; Kartha; Turnbull; Scheuerl, Shona L.; Naismith, James H.; Schenkman, Sergio; Field, Robert A.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 2 p. 141 - 144
反应条件
tetra(n-butyl)ammonium hydrogensulfate; sodium carbonate in ethyl acetate 1 h; Ambient temperature;
参考文献
Cao; Meunier; Andersson; Letellier; Roy
Tetrahedron Asymmetry, 1994 , vol. 5, # 11 p. 2303 - 2312
反应条件
1: 71 percent / ethanol / Ambient temperature; in dark 2: 57 percent / NaI / dimethylformamide / 6 h / 110 °C View Scheme
参考文献
Marra, Alberto; Sinay, Pierre
Carbohydrate Research, 1989 , vol. 187, p. 35 - 42
