2-氨基苯并[d]噻唑-7-羧酸乙酯合成路线 （共 7 条）
参考文献
Wel'tman
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1956 , vol. 22, p. 363,365
Chem.Abstr., 1957 , p. 4358
反应条件
3-thioureido-benzoic acid ethyl ester in chloroform; acetic acid
T=20 - 70°C; 17.5 h; Heating / reflux;
参考文献
Memory Pharmaceuticals Corporation
Patent: WO2004/29050 A1, 2004 ;
Location in patent: Page 68 ;
WO 2004/029050 A1
反应条件
sodium hydrogencarbonate in tetrahydrofuran; water; ethyl acetate
参考文献
MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2005/92890 A2, 2005 ;
Location in patent: Page/Page column 72 ;
WO 2005/092890 A2
反应条件
bromine; chlorobenzene
参考文献
Wel'tman
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1956 , vol. 22, p. 363,365
Chem.Abstr., 1957 , p. 4358
反应条件
1: concentrated H2SO4; chlorobenzene
2: bromine; chlorobenzene
View Scheme
参考文献
Wel'tman
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1956 , vol. 22, p. 363,365
Chem.Abstr., 1957 , p. 4358
反应条件
isopentyl nitrite in tetrahydrofuran
4 h; Heating / reflux;
参考文献
MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2005/92890 A2, 2005 ;
Location in patent: Page/Page column 71 ;
WO 2005/092890 A2
反应条件
ethanol; hydrazine hydrate
参考文献
Wel'tman
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1956 , vol. 22, p. 363,365
Chem.Abstr., 1957 , p. 4358
