in tetrahydrofuran T=180°C; 1 h; microwave irradiation;

1: 2-bromo-N-(2,6-dimethylphenyl)aniline With n-butyllithium in diethyl ether; hexane T=-35 - 20°C; 2: chloro-diphenylphosphine in diethyl ether; hexane; water T=-35 - 20°C;

1.1: palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether; sodium t-butanolate / toluene / 72 h / 95 °C / Inert atmosphere; sealed 2.1: n-butyllithium / diethyl ether; hexane / -35 - 20 °C 2.2: -35 - 20 °C View Scheme

1.1: palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether; sodium t-butanolate / toluene / 72 h / 95 °C / Inert atmosphere; sealed 2.1: n-butyllithium / diethyl ether; hexane / -35 - 20 °C 2.2: -35 - 20 °C View Scheme