tetrakis(triphenylphosphine) palladium(0); copper(I) thiophene-2-carboxylate; potassium carbonate; 1,2-bis-(diphenylphosphino)ethane in tetrahydrofuran T=50°C; Liebeskind-Srogl cross-coupling; 13 h; Inert atmosphere;

acetyl chloride in methanol 3 h; RefluxGreen chemistry; TemperatureTime; chemoselective reaction;