boron trifluoride-tetrahydrofuran complex in tetrahydrofuran T=20°C; 0.75 h;

lithium borohydride in tetrahydrofuran Heating / reflux;

1: With triethylamine; isobutyl chloroformate in dichloromethane T=0 - 20°C; 2 h; 2: With sodium tetrahydroborate in tetrahydrofuran; water 1 h;

sodium borohydride; boron trifluoride-diethyl ether complex in tetrahydrofuran; water

sulfuric acid in methanol 2 h; Reflux;

glucose dehydrogenase; β-D-glucopyranose; beta-nicotinamide adeninedinucleotide phosphatedisodium salt; catalase from Micrococcus lysodeikticus; cytochrome P450 BM3 monooxygenase from Bacillus megaterium F87A, L188C double mutant; potassium chloride; oxygen; tris(hydroxymethyl)methylamine hydrochloride in aq. phosphate buffer; dimethyl sulfoxide T=30°C; pH=7.5; 24 h; Green chemistryEnzymatic reaction; Reagent/catalyst; regioselective reaction;

calcium carbonate in 1,4-dioxane; water Heating;

1: thionyl chloride / 0 - 20 °C 2: sodium hydroxide / methanol / 20 °C 3: borane-THF / tetrahydrofuran / 0 - 20 °C / Inert atmosphere View Scheme

1: With methanol; sodium hydroxide; water T=20°C; 16 h; 2: With hydrogenchloride; water pH=1;

pyridinium chlorochromate in dichloromethane T=20°C; 3 h;