(E)-4-(4-羟基苯乙烯)吡啶合成路线 （共 10 条）
反应条件
acetic anhydride
24 h; Heating;
参考文献
Koopmans, Carsten; Ritter, Helmut
Journal of the American Chemical Society, 2007 , vol. 129, # 12 p. 3502 - 3503
反应条件
hydrogenchloride
6 h; Heating;
参考文献
Mikes, Frantisek; Labsky, Jiri; Vyprachticky, Drahomir; Chalabala, Jiri
Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 9 p. 2226 - 2232
反应条件
1: 120 °C
2: aq. NaHCO3 / ethanol
View Scheme
参考文献
Kumar, Uday; Kato, Takashi; Frechet, Jean M. J.
Journal of the American Chemical Society, 1992 , vol. 114, # 17 p. 6630 - 6639
反应条件
1: 120 °C
2: aq. NaHCO3 / ethanol
View Scheme
参考文献
Kumar, Uday; Kato, Takashi; Frechet, Jean M. J.
Journal of the American Chemical Society, 1992 , vol. 114, # 17 p. 6630 - 6639
反应条件
boron tribromide in dichloromethane
T=-10 - 0°C;
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
2: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 94.4 percent / LiAlH4 / diethyl ether / 4 h / Heating
2: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C
3: 4 h / Heating
4: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
5: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 4 h / Heating
2: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
3: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C
2: 4 h / Heating
3: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
4: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 95.3 percent / K2CO3 / acetone / 3 h / Heating
2: 94.4 percent / LiAlH4 / diethyl ether / 4 h / Heating
3: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C
4: 4 h / Heating
5: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
6: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
