2-甲氧基-4-硝基-5-氟苯甲醛合成路线 （共 2 条）
反应条件
Multi-step reaction with 5 steps 1: 90 percent / HNO3; H2SO4 / 0.5 h / 0 °C2: 85 percent / BBr3 / CH2Cl2 / 18 h / 0 - 20 °C3: 90 percent / K2CO3 / acetone / 1 h / Heating4: CrO3; H2SO4; AcOH / 0 - 10 °C5: aq. HCl / dioxane / Heating
参考文献
Iwanowicz, Edwin J.; Watterson, Scott H.; Guo, Junqing; Pitts, William J.; Murali Dhar; Shen, Zhongqi; Chen, Ping; Gu, Henry H.; Fleener, Catherine A.; Rouleau, Katherine A.; Cheney, Daniel L.; Townsend, Robert M.; Hollenbaugh, Diane L. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 12 p. 2059 - 2063
反应条件
Multi-step reaction with 4 steps 1: 85 percent / BBr3 / CH2Cl2 / 18 h / 0 - 20 °C2: 90 percent / K2CO3 / acetone / 1 h / Heating3: CrO3; H2SO4; AcOH / 0 - 10 °C4: aq. HCl / dioxane / Heating
参考文献
Iwanowicz, Edwin J.; Watterson, Scott H.; Guo, Junqing; Pitts, William J.; Murali Dhar; Shen, Zhongqi; Chen, Ping; Gu, Henry H.; Fleener, Catherine A.; Rouleau, Katherine A.; Cheney, Daniel L.; Townsend, Robert M.; Hollenbaugh, Diane L. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 12 p. 2059 - 2063
