1-(4-(4-溴苯基)哌嗪-1-基)乙酮合成路线 (共 5 条)
反应条件
1: 1-(4-bromo-phenyl)-piperazine With sodium hydrogencarbonate in water; ethyl acetate
2: acetic anhydride T=20°C; 2 h;
参考文献
Dainippon Pharmaceutical Co., Ltd.
Patent: EP1559707 A1, 2005 ;
Location in patent: Page/Page column 25 ;
反应条件
1: butan-1-ol
2: benzene
View Scheme
参考文献
Prelog; Blazek
Collection of Czechoslovak Chemical Communications, 1934 , vol. 6, p. 211,218
反应条件
1: butan-1-ol
2: benzene
View Scheme
参考文献
Prelog; Blazek
Collection of Czechoslovak Chemical Communications, 1934 , vol. 6, p. 211,218
参考文献
Prelog; Blazek
Collection of Czechoslovak Chemical Communications, 1934 , vol. 6, p. 211,218
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran
T=20°C; 24 h;
2: With hydrogenchloride in tetrahydrofuran; water
1 h; Heating / reflux;
参考文献
Dainippon Pharmaceutical Co., Ltd.
Patent: EP1559707 A1, 2005 ;
Location in patent: Page/Page column 25 ;