4-苯基-1,3-二氢-2H-咪唑-2-酮合成路线 （共 16 条）
反应条件
acetic acid; platinum Hydrogenation;
参考文献
Wilk; Close
Journal of Organic Chemistry, 1950 , vol. 15, p. 1020
反应条件
sodium acetate; palladium diacetate in dimethyl sulfoxide
T=80°C; 6 h;
参考文献
Lu, Jianming; Tan, Xianghui; Chen, Chuo
Journal of the American Chemical Society, 2007 , vol. 129, # 25 p. 7768 - 7769
反应条件
in water
T=70 - 80°C; 4 h;
参考文献
Calis; Dalkara; Ertan
Arzneimittel-Forschung/Drug Research, 1992 , vol. 42, # 5 p. 592 - 594
反应条件
in ethanol; chloroform
参考文献
DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD.
Patent: EP1021437 B1, 2001 ;
反应条件
ammonium acetate in acetic acid
3 h; Heating;
参考文献
Zav'yalov, S. I.; Sitkareva, I. V.; Ezhova, G. I.; Dorofeeva, O. V.; Zavozin, A. G.; Rumyantseva, E. E.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 6 p. 1297 - 1299
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 6 p. 1435 - 1437
反应条件
ammonium hydroxide in methanol
3 h; Heating;
参考文献
Shvaika, O. P.; Korotkikh, N. I.; Chervinskii, A. Yu.; Artemov, V. N.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, # 8 p. 1533 - 1543
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 8 p. 1728 - 1739
反应条件
in N,N-dimethyl-formamide
T=105°C; 72 h;
参考文献
Crank, George; Khan, Humaid R.
Australian Journal of Chemistry, 1985 , vol. 38, # 3 p. 447 - 458
反应条件
barium dihydroxide; ethanol
参考文献
Duschinsky; Dolan
Journal of the American Chemical Society, 1946 , vol. 68, p. 2350,2353
反应条件
ammonium hydroxide; acetic acid
Heating;
参考文献
Zav'yalov, S. I.; Sitkareva, I. V.; Ezhova, G. I.; Dorofeeva, O. V.; Zavozin, A. G.; Rumyantseva, E. E.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 6 p. 1297 - 1299
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 6 p. 1435 - 1437
反应条件
T=160°C; 0.166667 h; Neat (no solvent);
参考文献
Melnicky, Radek; Kvapil, Lubomir; Slezar, Petr; Grepl, Martin; Hlavac, Jan; Lycka, Antonin; Hradil, Pavel
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1437 - 1443
